Cutaneous Metastasis in Patient With Relapse Case of Primary Testicular Lymphoma

TL;DR

A patient with a history of testicular lymphoma experienced a rare case of cutaneous metastasis after 8 years of remission.

Contribution

This case report highlights a rare instance of cutaneous metastasis from testicular lymphoma with a long remission period.

Findings

Cutaneous metastasis occurred 8 years after treatment for primary testicular lymphoma.

Immunohistochemical markers confirmed metastasis from the original B cell lymphoma.

Skin lesions presented as erythematous papules and plaques on the chest.

Abstract

Non‐Hodgkin's lymphoma originates in the lymphatic system, specifically affecting B or T lymphocytes. Non‐Hodgkin's lymphoma of the testis is highly aggressive extranodal lymphoma originating from the testicles, constituting 1%–2% of all non‐Hodgkin's lymphoma cases. Relapse is reported in non‐Hodgkin's lymphoma of the testes, commonly in the contralateral testis and central nervous system, occurring within 1–2 years from diagnosis of primary lymphoma. Skin metastases occur in 6% to 13% of testicular lymphoma. Diffuse large B‐cell lymphoma is the most common type of testicular lymphoma, typically expressing CD19, CD20, CD22, CD79a, and PAX5 markers. Hereby, we have presented a case of cutaneous metastasis in a patient who underwent remission for 8 years following the treatment of primary testicular lymphoma. Identical immunohistochemical markers from the testis and skin lesion suggested cutaneous metastasis of testicular B cell lymphoma.

A 72 years male with cutaneous metastatic lesions presenting as multiple erythematous papules and plaques over chest. He had past history of primary testicular lymphoma and was treated with orchidectomy and chemotherapy.

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