# Psychiatric Comorbidities Associated with Food Addiction in Post-Bariatric Patients: Toward Personalized Mental Health Screening and Postoperative Care

**Authors:** Ligia Florio, Maria Olivia Pozzolo Pedro, Kae Leopoldo, Maria Amalia Accari Pedrosa, João Mauricio Castaldelli-Maia

PMC · DOI: 10.3390/jpm15070313 · 2025-07-14

## TL;DR

This study finds that food addiction in people who had bariatric surgery is strongly linked to several mental health disorders, suggesting a need for personalized mental health care after surgery.

## Contribution

The study identifies strong associations between food addiction and multiple psychiatric disorders in post-bariatric patients, supporting the use of food addiction as a marker for mental health risk assessment.

## Key findings

- Food addiction was present in 51% of post-bariatric patients.
- Food addiction was strongly associated with bulimia nervosa, generalized anxiety disorder, and obsessive–compulsive disorder.
- The findings suggest food addiction could serve as a clinical marker for personalized mental health monitoring after bariatric surgery.

## Abstract

Background: Food addiction (FA) is an emerging construct that mirrors the behavioral and neurobiological characteristics of substance use disorders. Despite growing interest, its association with specific psychiatric disorders among bariatric patients remains understudied. Objective: Our aim was to examine the prevalence and strength of associations between FA and seven major psychiatric disorders in individuals who underwent bariatric surgery. Methods: In a sample of 100 post-bariatric patients referred for psychiatric evaluation, FA was assessed using the modified Yale Food Addiction Scale 2.0 (mYFAS 2.0), and psychiatric disorders were diagnosed using the Mini International Neuropsychiatric Interview (MINI). Logistic regression models were used to estimate adjusted odds ratios (aORs) for the association between FA and each psychiatric disorder, controlling for sex, age, body mass index (BMI), employment status, the number of children, clinical comorbidities, physical activity, family psychiatric history, and region of residence. Results: FA was present in 51% of the sample. Descriptive analyses revealed a significantly higher prevalence of major depressive disorder, panic disorder, generalized anxiety disorder, social anxiety disorder, agoraphobia, obsessive–compulsive disorder, and bulimia nervosa among individuals with FA. Multivariate models showed robust associations between FA and bulimia nervosa (aOR = 19.42, p < 0.05), generalized anxiety disorder (aOR = 2.88, p < 0.05), obsessive–compulsive disorder (aOR = 6.64, p < 0.05), agoraphobia (aOR = 3.14, p < 0.05), social anxiety disorder (aOR = 4.28, p < 0.05) and major depressive disorder (aOR = 2.79, p < 0.05). Conclusions: FA is strongly associated with a range of psychiatric comorbidities in post-bariatric patients, reinforcing the need for comprehensive mental health screening in this population. These findings underscore the potential role of FA as a clinical marker for stratified risk assessment, supporting more personalized approaches to mental health monitoring and intervention following bariatric surgery.

## Linked entities

- **Diseases:** major depressive disorder (MONDO:0002009), panic disorder (MONDO:0005383), generalized anxiety disorder (MONDO:0001942), social anxiety disorder (MONDO:0001247), agoraphobia (MONDO:0003709), obsessive–compulsive disorder (MONDO:0008114), bulimia nervosa (MONDO:0005452)

## Full-text entities

- **Diseases:** substance use disorders (MESH:D019966), panic disorder (MESH:D016584), FA (MESH:D000073932), social anxiety disorder (MESH:D000072861), bulimia nervosa (MESH:D052018), obsessive-compulsive disorder (MESH:D009771), Psychiatric (MESH:D001523), agoraphobia (MESH:D000379), generalized anxiety disorder (MESH:C000726808), major depressive disorder (MESH:D003865)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12300192