Structural Characterization and Anti-Ultraviolet Radiation Damage Activity of Polysaccharides from Helianthus annuus (Sunflower) Receptacles
Xiaochun Chen, Zhiying Wei, Xiaoying Mo, Yantong Lu, Guangjuan Pan, Zhenzhen Pan, Yaohua Li, Hui Tian, Xiaojiao Pan
TL;DR
This study explores the potential of sunflower receptacle polysaccharides as natural, eco-friendly ingredients for UV-protective cosmetics.
Contribution
A new purified polysaccharide (HRP-1) from sunflower receptacles is isolated and shown to protect against UV-induced skin damage.
Findings
HRTP suppressed reactive oxygen species and inflammatory cytokines in UV-exposed HaCaT cells.
HRTP downregulated MMPs and exhibited moisturizing properties, suggesting UV-protective and skin-nourishing effects.
The study highlights sunflower receptacle polysaccharides as sustainable biomaterials for sunscreen formulations.
Abstract
Helianthus annuus L. (H. annuus) receptacles, a major agricultural by-product generated during seed processing, are currently underutilized. This study aimed to explore the valorization potential of this by-product by extracting H. annuus receptacles total polysaccharides (HRTP) and characterizing their potential as natural ingredients in ultraviolet (UV)-protective cosmetics. A new purified polysaccharide named H. annuus receptacles polysaccharide-1 (HRP-1) was isolated, likely exhibiting a backbone of alternating →4)-α-D-GalA-(1→ and →4)-α-D-GalA(6-OCH3)-(1→ units, with a weight-average molecular weight (Mw) of 163 kDa. HRTP demonstrated significant protective effects against UV-induced damage in human immortalized keratinocyte (HaCaT) cells by suppressing intracellular reactive oxygen species (ROS) levels and downregulating MAPK-p38/ERK/JNK pathways, thereby inhibiting inflammatory…
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Taxonomy
TopicsSeaweed-derived Bioactive Compounds · Polysaccharides and Plant Cell Walls · Phytochemicals and Antioxidant Activities