# Optimising stakeholder engagement during intervention planning and development using the Person-Based Approach: the example of an online FeNO-guided asthma management intervention in primary care

**Authors:** Marta Santillo, Kate Morton, Michelle Helena Van Velthoven, Lucy Yardley, Mike Thomas, Kay Wang, Ben Ainsworth, Sarah Tonkin-Crine

PMC · DOI: 10.1038/s41533-025-00435-9 · 2025-07-25

## TL;DR

This paper explains how stakeholder engagement using the Person-Based Approach helped develop an online asthma management intervention focused on FeNO testing in primary care.

## Contribution

The study demonstrates a novel application of the Person-Based Approach to optimize stakeholder involvement in behavioral intervention development.

## Key findings

- Stakeholder feedback identified new barriers and facilitators to FeNO test adoption in asthma reviews.
- Involving stakeholders led to optimized intervention materials, including tailored online training and patient leaflets.
- The PBA approach facilitated in-depth interpretation of qualitative data during intervention planning.

## Abstract

This paper is a detailed methodological analysis of how the PBA approach was used as part of the DEFINE programme, in the planning and development of a behavioural intervention to support the use of Fractional Exhaled Nitric Oxide (FeNO) in informing asthma management in primary care asthma reviews. It offers detailed research insights into how using the PBA approach facilitates the development of methodologies for stakeholder engagement and intervention development research, in line with the recent MRC framework. Two stakeholder workshops were organised during the intervention planning and development phases. The patient stakeholders were diverse in age, gender, and asthma severity, while the clinical stakeholders were diverse in clinical role and level of experience using FeNO. The research team mapped how the stakeholders’ feedback complemented the core research team-based activities during the two stages of intervention planning and development, and what the outcomes of such engagement were. The five PBA intervention development activities in which stakeholderswere involved were: (1) Understanding target behaviours; (2) Identifying how to promote engagement with target behaviours; (3) Ensuring anticipated mechanisms of action are taken into account in planning intervention components; (4) Developing intervention content; and (5) Identifying the best intervention content and implementation. Outcomes of involving stakeholder in the 5 intervention development activities were: in depth interpretation on the qualitative work,new barriers and facilitators to the target behaviour of adoption and use of FeNO test during asthma reviews, and optimisation of intervention materials through in-depth tailoring of the online training and patient leaflet.

## Linked entities

- **Diseases:** asthma (MONDO:0004979)

## Full-text entities

- **Diseases:** asthma (MESH:D001249)
- **Chemicals:** Nitric Oxide (MESH:D009569)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12297380/full.md

---
Source: https://tomesphere.com/paper/PMC12297380