# A Rare Case of Cold Antibody-Mediated Autoimmune Haemolytic Anaemia in Early Systemic Lupus Erythematosus

## TL;DR

This paper presents a rare case of a teenager with lupus and a type of anemia caused by the immune system attacking red blood cells.

## Contribution

The novelty lies in highlighting the diagnostic challenges of SLE presenting with AIHA in adolescents.

## Key findings

- A 16-year-old female presented with symptoms including weakness, joint pain, and anemia.
- The case underscores the need for prompt autoimmune and hematologic evaluation in such patients.

## Abstract

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterised by autoantibody production, leading to multiorgan inflammation and tissue damage. Autoimmune haemolytic anaemia (AIHA) is a recognised haematologic complication of SLE. This report describes a 16-year-old female who presented with four weeks of generalised weakness, polyarthralgia, recurrent syncopal episodes, and Raynaud’s phenomenon. This case highlights the diagnostic challenges of SLE presenting with AIHA, underscoring the importance of prompt, comprehensive autoimmune and haematologic evaluation in adolescents with unexplained anaemia and multi-system involvement.