# Combining Pulsed and Conventional Radiofrequency Ablation for Resistant Morton’s Neuroma: A Case Report and Literature Review

**Authors:** Karim Hemati, Sajede Salehi, Parnian Hemati

PMC · DOI: 10.5812/aapm-161482 · 2025-05-19

## TL;DR

A 61-year-old man with resistant Morton’s neuroma experienced long-term pain relief using a combination of pulsed and conventional radiofrequency treatments.

## Contribution

This is the first reported case using a combined pulsed and conventional radiofrequency approach for Morton’s neuroma.

## Key findings

- The patient reported significant pain reduction with NRS scores of 1 at two weeks and one month, and 2 at seven months.
- The combined PRF and CRF treatment provided a viable alternative to surgery for refractory Morton’s neuroma.
- The treatment protocol involved sequential temperatures of 42°C, 60°C, and 70°C for specific durations.

## Abstract

Morton's neuroma is a painful, degenerative neuropathy that is initially managed with conservative treatments. In refractory cases, surgical excision is typically indicated. Minimally invasive percutaneous procedures provide a viable alternative to surgery.

While both pulsed radiofrequency (PRF) and conventional radiofrequency (CRF) have been individually reported as effective treatments for Morton’s neuroma, we aim to utilize a combination of PRF and CRF for pain management.

We report the case of a 61-year-old male with a five-year history of right foot Morton’s neuroma, presenting with severe pain that was refractory to conservative management, including multiple corticosteroid injections. Radiofrequency was performed as follows: 5 minutes at 42°C, 1 minute at 60°C, and 1 minute at 70°C.

The patient experienced significant pain relief, with follow-up Numerical Rating Scale (NRS) of 1 at two weeks, 1 at one month, and 2 at seven months post-treatment.

This case suggests that the combined application of PRF and CRF may serve as a promising alternative for managing refractory Morton’s neuroma.

## Full-text entities

- **Diseases:** pain (MESH:D010146), degenerative neuropathy (MESH:D019636), Morton's Neuroma (MESH:D000070607)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12296642