# Seamless meningioma resection in a patient with coexisting myoclonic epilepsy and sporadic Pick’s disease

**Authors:** Jose Maaz, Carlos Diaz, Marcos Orellana, Ricardo A Caravantes

PMC · DOI: 10.1093/omcr/omaf116 · 2025-07-27

## TL;DR

A 62-year-old man with myoclonic epilepsy and Pick’s disease underwent successful meningioma surgery, showing the importance of interdisciplinary care.

## Contribution

This case highlights the successful surgical management of a meningioma in a patient with complex overlapping neurological conditions.

## Key findings

- Neuronavigation technology enabled complete meningioma resection in a patient with sporadic Pick’s disease.
- Postoperative outcomes showed resolution of syncope and improved gait.
- The case emphasizes the need for interdisciplinary approaches in complex neurological presentations.

## Abstract

We report the case of a 62-year-old male presenting with progressive gait disturbances, recurrent syncope, and episodes of myoclonic epilepsy over three months, with underlying sporadic Pick’s disease diagnosed clinically. Imaging revealed a well-defined, extra-axial tumor in the right parietal region, consistent with a meningioma. Surgical intervention using neuronavigation technology facilitated a complete tumor resection. The patient’s postoperative course was stable, with a resolution of syncope and improvement in gait. This case underscores the importance of interdisciplinary management in patients with overlapping neurological conditions and highlights the challenges posed by multifaceted clinical presentations.

## Linked entities

- **Diseases:** myoclonic epilepsy (MONDO:0100577)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), meningioma (MESH:D008579), gait disturbances (MESH:D020233), myoclonic epilepsy (MESH:D004831), Pick's disease (MESH:D020774), syncope (MESH:D013575)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12296379/full.md

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Source: https://tomesphere.com/paper/PMC12296379