# COVID-19 Cerebral Vasculitis With Extensive Involvement of Anterior Circulation and Sparing of Posterior Circulation

**Authors:** Thomas E Kent, Sohil H Patel, Prem P Batchala, Joseph H Donahue, Thomas J Eluvathingal Muttikkal

PMC · DOI: 10.7759/cureus.86818 · 2025-06-26

## TL;DR

This paper reports a case of cerebral vasculitis in a COVID-19 patient affecting the brain's anterior blood vessels but not the posterior ones.

## Contribution

The study highlights a unique pattern of vasculitis in COVID-19 patients with stroke, emphasizing the role of vessel wall imaging in diagnosis.

## Key findings

- A patient with COVID-19 developed anterior circulation vasculitis and ischemic stroke.
- Posterior circulation was unaffected in the same patient.
- Vessel wall imaging helped differentiate vasculitis from other stroke causes.

## Abstract

COVID-19 infection is associated with stroke due to various proposed mechanisms, including cerebral vasculitis, arterial and venous thrombosis. Vessel wall imaging, although not pathognomonic, interpreted in the appropriate clinical context and supportive laboratory findings, can help clarify the diagnosis and differentiate the etiology from other mechanisms of CNS involvement. We describe a patient with extensive anterior circulation vasculitis and ischemic stroke in the setting of COVID-19, with sparing of the posterior circulation.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096), ischemic stroke (MONDO:1060198)

## Full-text entities

- **Diseases:** stroke (MESH:D020521), Cerebral Vasculitis (MESH:D020293), arterial and venous thrombosis (MESH:D020246), COVID-19 (MESH:D000086382), ischemic stroke (MESH:D002544), anterior circulation vasculitis (MESH:D020520)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12296368/full.md

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Source: https://tomesphere.com/paper/PMC12296368