# Post-COVID Surge in Pediatric Emergency Department Accesses for Psychiatric Conditions: A Retrospective Analysis of Anxiety, Self-Injury Behaviors, and Psychomotor Agitation

**Authors:** Tommaso Bellini, Silvia Merlo, Andrea Lacovara, Sara Uccella, Martino Diana, Martina Turone, Carolina Viglietti, Barbara Tubino, Lino Nobili, Pasquale Striano, Emanuela Piccotti, Andrea Moscatelli, Laura Siri

PMC · DOI: 10.3390/jcm14144814 · 2025-07-08

## TL;DR

This study found a significant increase in pediatric emergency department visits for psychiatric issues like anxiety and self-injury after the start of the COVID-19 pandemic.

## Contribution

The study provides new evidence on the post-COVID surge in pediatric psychiatric emergencies and highlights the need for improved mental health care protocols.

## Key findings

- Self-injury behaviors increased from 3.6 to 15.1 per 10,000 visits post-COVID.
- Psychomotor agitation cases rose from 9.4 to 17.8 per 10,000 visits post-COVID.
- Anxiety disorder visits increased from 17.7 to 21.6 per 10,000 visits post-COVID.

## Abstract

Background: The COVID-19 pandemic has had a profound impact on pediatric mental health, contributing to a global surge in psychiatric emergencies among children and adolescents. This study aimed to evaluate trends in pediatric emergency department (PED) visits for three key psychiatric conditions—anxiety disorders (ADs), self-injury behaviors (SIBs), and psychomotor agitation (PMA)—before and after the onset of the COVID-19 pandemic. Methods: We conducted a retrospective observational study at a tertiary pediatric hospital in Italy, analyzing all psychiatric presentations to the PED from 1 January 2018 to 31 December 2024. The data were divided into pre-COVID and post-COVID periods and included patient demographics, recurrence of visits, clinical features, hospital admissions, and pharmacological management. Diagnoses were confirmed by chart review. Results: Of 233,867 total PED visits, 1082 were due to primary psychiatric concerns. A marked increase in visits was observed postCOVID: SIB incidence rose from 3.6 to 15.1 per 10,000 visits (p < 0.0001), PMA from 9.4 to 17.8 (p < 0.0001), and AD from 17.7 to 21.6 (p = 0.018). SIB cases showed increased recurrence (from 3.4% to 27.4%, p = 0.004) and greater pharmacological intervention, whereas PMA was associated with a rise in heteroaggression (from 14.3% to 39.8%, p < 0.0001). Pharmacological treatment remained largely consistent, with benzodiazepines and neuroleptics most frequently used. The emerging use of intranasal ketamine was noted in select cases. Conclusions: This study highlights the increasing burden of pediatric psychiatric emergencies in the wake of the COVID-19 pandemic. The findings underscore the urgent need to implement standardized emergency care protocols, strengthen outpatient mental health services, and develop pediatric-specific pharmacological guidelines to improve outcomes in this vulnerable population.

## Full-text entities

- **Diseases:** COVID (MESH:D000086382), Anxiety (MESH:D001007), PMA (MESH:D011595), AD (MESH:D000544), SIBs (MESH:D012652), ADs (MESH:D001008), Psychiatric Conditions (MESH:D001523), Post-COVID (MESH:D000094024)
- **Chemicals:** ketamine (-), benzodiazepines (MESH:D001569)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12295347/full.md

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Source: https://tomesphere.com/paper/PMC12295347