# Thoracolumbar Kyphosis Is a Risk Factor for Proximal Junctional Kyphosis After Isolated Posterior Surgery for Lenke-5C Curvature

**Authors:** Nobuki Tanaka, Tetsuro Ohba, Kotaro Oda, Marina Katsu, Hayato Takei, Kai Mizukami, Go Goto, Hirotaka Haro

PMC · DOI: 10.3390/jcm14144913 · Journal of Clinical Medicine · 2025-07-10

## TL;DR

This study finds that thoracolumbar kyphosis before surgery increases the risk of proximal junctional kyphosis after spinal surgery for Lenke-5C curvature.

## Contribution

The study identifies preoperative thoracolumbar kyphosis as a novel risk factor for PJK in Lenke-5C scoliosis patients undergoing posterior surgery.

## Key findings

- PJK occurred in 55.3% of patients after isolated posterior surgery for Lenke-5C curvature.
- Patients with preoperative positive thoracolumbar kyphosis had an 83.3% PJK occurrence rate.
- Preoperative sagittal alignment parameters correlated with postoperative PJK development.

## Abstract

Background/Objectives: This study aimed to examine the occurrence and risk factors for proximal junctional kyphosis (PJK) in relation to preoperative sagittal alignment, particularly the shape of thoracolumbar kyphosis (TLK) and the proportion of lumbar lordosis. Methods: We recruited 38 consecutive patients with adolescent idiopathic scoliosis (AIS) who underwent isolated posterior fusion. Participants were categorized according to the presence or absence of PJK at 1 year postoperatively (PJK+ or non-PJK) and by preoperative TLK status (positive or negative; pre-TLK+ or pre-TLK, respectively). We compared spinal parameters preoperatively, immediately postoperatively, and at 1 year postoperatively between groups. Results: Among the 38 participants, PJK occurred in 21 patients (55.3%). The PJK group had significantly larger preoperative TLK and LDI values and decreased postoperative TLK and LDI. Simple linear regression revealed a moderate positive correlation between ΔPJA and preoperative TLK as well as a fair positive correlation between ΔPJA and changes in TLK and LDI. The prevalence of PJK was high (83.3%) in the pre-TLK+ group (24 patients), and preoperative LDI was significantly larger compared with the pre-TLK group. However, TLK and LDI were significantly decreased after surgery in the pre-TLK+ group. Conclusions: Patients with Lenke-5C curvature who exhibit positive preoperative TLK are at a very high risk of developing PJK after isolated posterior surgery. Preoperative sagittal alignment should be considered when planning the extent of sagittal correction.

## Linked entities

- **Diseases:** adolescent idiopathic scoliosis (MONDO:0005488)

## Full-text entities

- **Diseases:** AIS (OMIM:181800), PJK (MESH:D007738)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12295053/full.md

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Source: https://tomesphere.com/paper/PMC12295053