# Associations Between Metabolic Risk Factors and Lung Function Among Adults in Northern Thailand: A Cross-Sectional Study

## TL;DR

This study explores how metabolic risk factors like high triglycerides and reduced walking ability are linked to worse lung function in adults from northern Thailand.

## Contribution

The study identifies the 6-minute walk test as a significant predictor of lung function impairment in a population with high metabolic and environmental risks.

## Key findings

- Higher triglyceride levels were associated with reduced FEV1 and FVC.
- Shorter 6-minute walk test distances were significantly linked to lung function impairment.
- The dual burden of metabolic disorders and air pollution in northern Thailand highlights the need for integrated health screening.

## Abstract

Background/Objectives: Lung function decline is influenced by metabolic risk factors (e.g., obesity, hyperglycemia, dyslipidemia) and environmental exposures (e.g., PM2.5), which may jointly contribute to airway inflammation and lung function impairment. This study aimed to investigate these associations in northern Thai adults and identify factors linked to lung function impairment. Methods: A cross-sectional study was conducted in San Pa Thong, Chiang Mai, Thailand, involving 137 adults. Data on metabolic indicators and spirometry were collected. Statistical analyses included Spearman’s correlation, multivariable linear regression, and logistic regression. Results: Higher triglyceride levels and shorter 6-min walk test (6MWT) distances were associated with reduced forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). Only 6MWT distance remained a significant factor for lung function impairment in logistic regression (adjusted OR = 0.763, 95% CI: 0.588–0.990, p = 0.042). Conclusions: Combining metabolic and respiratory assessments may improve early detection of lung function impairment in high-risk populations, particularly given the dual burden of metabolic disorders and air pollution in northern Thailand. These findings support the integration of metabolic and respiratory screening in community health programs to enhance preventive strategies.