Myxoid Liposarcoma of the Thigh in Early Puerperium—Rare Case Report and Narrative Review

TL;DR

A rare case of myxoid liposarcoma in a woman's thigh during the early postpartum period is reported and reviewed.

Contribution

This is the first reported case of myxoid liposarcoma diagnosed during the puerperium.

Findings

Myxoid liposarcoma is rare in women and even rarer during pregnancy or the puerperium.

Early detection and proper treatment are crucial for improving outcomes in such cases.

The case highlights the importance of considering sarcomas in differential diagnoses during postpartum periods.

Abstract

Background: Liposarcoma (LPS) is a rare malignant tumor, but it is also one of the most common adult soft-tissue sarcomas. Myxoid liposarcoma (MLPS) accounts for 30% of all LPS cases. Diagnosis during pregnancy and the puerperium is very rarely reported, and only a few cases have been reported in the thigh. Case presentation: We report the case of a 36-year-old female patient on the 11th day of the puerperium after a cesarean section. The patient presented to the gynecology ward owing to the sudden appearance of a tumor in the medial part of her right thigh. The lesion was non-painful, mobile, soft, approximately 20 cm in diameter, and protruded above the level of the rest of the thigh surface. A suspicion of hematoma was raised. The final diagnosis was high-grade MLPS. Conclusions: An MLPS diagnosis is uncommon in female patients and even rarer during pregnancy. This case represents a novel occurrence, as the first instance in which symptoms manifested during the puerperium. Proper treatment and early detection could improve disease outcomes.

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