Chest Wall Chondromyxoid Fibroma: A case report and literature review

TL;DR

A rare case of chest wall chondromyxoid fibroma in a 28-year-old woman is reported, highlighting its diagnosis and treatment.

Contribution

The paper presents a new case report and literature review to guide clinical decisions for this rare tumor.

Findings

CMF was diagnosed and successfully resected using video-assisted thoracic surgery.

The case contributes to understanding the radiological and histopathological features of CMF.

The report includes data from 11 other cases to support clinical decision-making.

Abstract

Chondromyxoid fibromas (CMFs) are rare tumours that comprise less than 2% of benign bone tumours; approximately 5–7.9% occur in the ribs. We report a 28-year-old female patient with CMF in the 4th rib that presented to a tertiary care hospital in Muscat, Oman, in 2023. She complained of pain in the right posterior chest wall for 6 months. A chest computed tomography showed posterior 4th rib expansile lesion measuring 3 × 2 cm without soft tissue involvement. A percutaneous biopsy suggested a diagnosis of chondomyxoid fibroma. The tumour was resected with a free-margin and assistance of video-assisted thoracic surgery approach. The diagnosis of CMF was confirmed postoperatively by histopathological studies. In terms of radiological feature, histopathological findings, and the treatment options, this data and the data of 11 other cases can contribute to guide the advancement of clinical decisions.

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