# Plastic Reconstruction of Upper Extremity Defects in Necrotizing Soft Tissue Infections

**Authors:** Karren M. Takamura, Jason J. Yoo

PMC · DOI: 10.3390/bioengineering12070718 · 2025-06-30

## TL;DR

This paper discusses reconstructive techniques for upper limb defects caused by severe soft tissue infections.

## Contribution

The paper provides a comprehensive overview of plastic surgery options for upper extremity defects after necrotizing infections.

## Key findings

- Soft tissue reconstruction options include dermal substitutes, local flaps, and free tissue transfer.
- Functional outcomes can be good following appropriate reconstruction techniques.
- Patient-specific factors guide the choice of reconstruction method.

## Abstract

Soft tissue reconstruction in patients with upper extremity necrotizing soft tissue infections (NSTIs) can be challenging; these defects can be large with exposed critical structures. Following appropriate source control and debridement, soft tissue reconstruction is based on size, exposed structures, medical co-morbidities and the physiologic status of the patient. There are multiple options for soft tissue coverage from local wound care to free tissue transfer. Dermal substitutes can help prepare a healthy wound bed that can later accept a skin graft. Local rotational flaps, distant pedicled flaps and free flaps are also options depending on the patient and the defect. Patients can have good functional outcomes after soft tissue reconstruction after upper extremity NSTI.

## Full-text entities

- **Diseases:** Defects (MESH:D000013), NSTIs (MESH:D018461)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12292493/full.md

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Source: https://tomesphere.com/paper/PMC12292493