# Real World Case Series: Integrated Skincare With Advanced RGN‐6 Serum

## TL;DR

A new skincare serum called RGN-6 was tested in combination with facial rejuvenation procedures to improve skin appearance in women with skin of color.

## Contribution

The study presents a real-world case series demonstrating the effectiveness of RGN-6 serum in post-procedure skincare for skin of color.

## Key findings

- Twice daily application of RGN-6 serum improved redness, fine lines, and skin tone in post-procedure patients.
- The serum was used in combination with energy-based facial rejuvenation procedures.
- Expert dermatologists observed visible improvements in skin appearance across Fitzpatrick skin types 3 to 6.

## Abstract

Skin aging is a multifactorial process with intrinsic and extrinsic factors that lead to visible signs of aging, including loss of skin elasticity, volume, dyspigmentation, wrinkles, fine lines, and dry and uneven skin. The advanced RGN‐6 serum is a patent‐pending, multi‐ingredient serum that has been developed to address 6 dimensions of skin regeneration and combat visible signs of aging. The six dimensions of skin regeneration include: (1) barrier re‐epithelialization, (2) redness and inflammation, (3) cellular energy stimulation, (4) elastin and collagen stimulation, (5) antioxidants, and (6) postinflammatory hyperpigmentation (PIH). To address these factors, the RGN‐6 serum contains six active ingredients: 1% eperuline, 0.2% ectoin, 10% glycorepair, 0.2% bioceramide 603, 3% acetyl tetrapeptide‐9, and 2% niacinamide. This multi‐ingredient serum works to simultaneously target the most common signs of aging.

To provide detailed evidence for multiple integrated skincare regimens using the advanced RGN‐6 serum in facial rejuvenation.

In this real‐world case series, 6 expert dermatologists with extensive experience in cosmetic and anti‐aging medicine shared and discussed patient cases of advanced RGN‐6 serum used in combination with energy‐based facial rejuvenation procedures in a subset of women with skin of color with Fitzpatrick skin types ranging from type 3 to type 6.

After the panel discussion, six patient cases were selected to best demonstrate the use of RGN‐6 serum postprocedure.

The panel experts agreed that twice daily application of the RGN‐6 serum led to improved signs of redness, fine lines, and skin tone and evenness in all postprocedure patients.