# Termination of atrial arrhythmia and restoration of sinus rhythm during pulsed field ablation with a pentaspline catheter in patients with persistent atrial fibrillation

**Authors:** Massimo Moltrasio, Saverio Iacopino, Francesco Solimene, Stefano Bianchi, Marco Schiavone, Sakis Themistoclakis, Antonio Rossillo, Matteo Bertini, Davide Zirolia, Mario Volpicelli, Gianluca Zingarini, Antonio Dello Russo, Maurizio Malacrida, Giulio Zucchelli, Claudio Tondo

PMC · DOI: 10.1093/europace/euaf144 · Europace · 2025-07-08

## TL;DR

This study explores using pulsed field ablation with a pentaspline catheter to treat persistent atrial fibrillation by terminating arrhythmia and restoring normal heart rhythm.

## Contribution

The novel use of a pentaspline catheter in pulsed field ablation for treating persistent atrial fibrillation is introduced.

## Key findings

- Pulsed field ablation with a pentaspline catheter terminates atrial arrhythmia.
- The procedure restores sinus rhythm in patients with persistent atrial fibrillation.

## Abstract

Clinical trial registration: Advanced TecHnologies For SuccEssful AblatioN of AF in Clinical Practice (ATHENA). URL: http://clinicaltrials.gov/Identifier: NCT05617456.

## Linked entities

- **Diseases:** persistent atrial fibrillation (MONDO:1030009)

## Full-text entities

- **Diseases:** atrial fibrillation (MESH:D001281), atrial arrhythmia (MESH:D001145)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12290877/full.md

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Source: https://tomesphere.com/paper/PMC12290877