# Parental Report of Signs of Anxiety and Depression in Children and Adolescents with and Without Disability in Middle- and Low-Income Countries: Meta-analysis of 44 Nationally Representative Cross-Sectional Surveys

**Authors:** Eric Emerson, Gwynnyth Llewellyn

PMC · DOI: 10.1007/s10578-023-01608-8 · Child Psychiatry and Human Development · 2023-10-04

## TL;DR

Children and adolescents with disabilities in low- and middle-income countries are more likely to show signs of anxiety and depression compared to their non-disabled peers.

## Contribution

This study provides the first meta-analysis of disability and emotional difficulties in children across 44 low- and middle-income countries.

## Key findings

- Children with disabilities are about 2.5 times more likely to show signs of anxiety or depression.
- The risk is highest in upper middle-income countries and lowest in low-income countries.
- Approximately 20% of children with frequent anxiety or depression also have a disability.

## Abstract

Population-based studies undertaken in high-income countries have indicated that children and adolescents with disabilities are more likely than their non-disabled peers to experience emotional difficulties such as anxiety and depression. Very little is known about the association between disability and emotional difficulties among children growing up in low and middle-income countries (LMICs). We aimed to estimate the strength of association between disability and two forms of emotional difficulties (anxiety, depression) in a range of LMICs and to determine whether the strength of this relationship was moderated by child age and gender. Secondary analysis of data collected in Round 6 of UNICEF’s Multiple Indicator Cluster Surveys undertaken in 44 LMICs (combined n = 349,421). Data were aggregated across countries by both mixed effects multi-level modelling and restricted maximum likelihood meta-analysis. Young people with disabilities, when compared with their non-disabled peers, were approximately two and a half times more likely to be reported by parents to show daily signs of either anxiety or depression. The level of risk among young people with disabilities was highest in upper middle-income countries and lowest in low-income countries. We estimated that approximately 20% of young people with frequent anxiety or depression also had a disability. All approaches to mental health interventions (from primary prevention to clinical interventions) need to make reasonable accommodations to their services to ensure that the young people with emotional difficulties who also have a disability are not ‘left behind’.

The online version contains supplementary material available at 10.1007/s10578-023-01608-8.

## Linked entities

- **Diseases:** anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** Anxiety (MESH:D001007), Depression (MESH:D003866), emotional difficulties (MESH:D051346), Disability (MESH:D009069)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12289834/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12289834/full.md

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Source: https://tomesphere.com/paper/PMC12289834