# An Interesting Presentation of Hypercalcaemia in a Middle-Aged Male

**Authors:** Aminah Patel, Rehan Siddique, Amber Khan

PMC · DOI: 10.7759/cureus.86682 · Cureus · 2025-06-24

## TL;DR

A middle-aged man with hypercalcaemia and kidney issues was eventually diagnosed with sarcoidosis after initial confusion with other conditions.

## Contribution

The paper presents a rare and complex case emphasizing the need to consider sarcoidosis in hypercalcaemia diagnoses.

## Key findings

- Hypercalcaemia and acute kidney injury were initially misattributed to mumps and Sjögren’s syndrome.
- Diagnosis of sarcoidosis was confirmed through imaging and skin biopsy showing non-caseating granulomas.
- The case underscores the diagnostic challenges of hypercalcaemia and the importance of considering granulomatous diseases.

## Abstract

A 41-year-old male presented to the Emergency Department with hypercalcaemia and acute kidney injury. He initially presented with bilateral parotid swelling which was treated as mumps. This was later investigated for suspected Sjögren’s syndrome, but further evaluation led to a diagnosis of sarcoidosis. Imaging confirmed extensive mediastinal and hilar lymphadenopathy, and a skin biopsy revealed non-caseating granulomas, confirming sarcoidosis. This case highlights the complexity of diagnosing hypercalcaemia and the importance of considering systemic granulomatous diseases like sarcoidosis in the differential diagnoses.

## Linked entities

- **Diseases:** acute kidney injury (MONDO:0002492), mumps (MONDO:0000989), sarcoidosis (MONDO:0008399)

## Full-text entities

- **Diseases:** mumps (MESH:D009107), granulomas (MESH:D006099), parotid swelling (MESH:D010309), lymphadenopathy (MESH:D008206), acute kidney injury (MESH:D058186), Sjogren's syndrome (MESH:D012859), systemic granulomatous diseases (MESH:C537295), sarcoidosis (MESH:D012507)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12289318/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12289318/full.md

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Source: https://tomesphere.com/paper/PMC12289318