# Follow-up of patients with myocardial ischemia without obstructive coronary lesions

## TL;DR

This study tracks patients with heart issues but no major artery blockages, finding that those with diabetes, heart disease family history, or kidney disease had worse outcomes.

## Contribution

The study provides insights into the long-term outcomes of patients with non-obstructive coronary lesions and identifies risk factors for adverse events.

## Key findings

- 80% cardiovascular event-free survival was observed over three years.
- Heart failure was the leading cause of re-hospitalization.
- Diabetes, family history of heart disease, and kidney disease were linked to higher event rates.

## Abstract

The presence of coronary lesions of less than 50% in patients with myocardial ischaemia is a common diagnosis in cardiac catheterisation laboratories. The aim of this study was to determine the clinical course of patients with myocardial ischaemia in the absence of obstructive coronary lesions.

A prospective analytical study was conducted in 110 patients of both sexes with documented myocardial ischaemia and coronary lesions of less than 50% on coronary angiography. The follow-up period was three years.

The mean age was 64.5 ± 7.2 years, with a predominance of females (57%). The most prevalent risk factors were hypertension (58.2%) and dyslipidaemia (44.5%). In 8.3% of cases, re-hospitalisation was required, with heart failure reported as the leading cause (6.5%). Cardiovascular event-free survival during follow-up was 80%, and was higher in patients without coronary lesions. A higher incidence of cardiovascular events was associated with diabetes mellitus, a family history of ischaemic heart disease, and chronic kidney disease.

Patients with myocardial ischaemia in the absence of obstructive coronary lesions experienced adverse events during follow-up, particularly those with diabetes mellitus, a family history of ischaemic heart disease, and chronic kidney disease.