# Integrating VYC‐12L With Energy‐Based Devices for Skin‐Quality Improvement: Global Expert Considerations for Safe and Effective Outcomes

## TL;DR

Combining VYC-12L with energy-based devices can improve skin quality when used safely and effectively according to expert guidance.

## Contribution

Provides expert-based guidance on integrating VYC-12L and energy-based devices for skin-quality improvement.

## Key findings

- Combining VYC-12L and EBDs offers synergistic benefits for skin quality improvement.
- Proper sequencing and aseptic technique are crucial when using both treatments together.
- Training and correct injection depth are essential for successful outcomes with VYC-12L.

## Abstract

Energy‐based devices (EBDs) and injectable hyaluronic acid gels, such as VYC‐12L, are each effective treatment modalities for improving skin quality.

To assess the rationale and potential benefits of adding VYC‐12L to EBD treatments, and consider how they can be practically integrated into a single treatment plan.

Eight clinicians with various specialties and extensive experience of these modalities completed a written questionnaire and were individually interviewed. Their collective clinical expertise and experience form the basis of this guidance.

Using both VYC‐12L and EBDs within a single treatment plan offers many potential benefits for improving skin quality—based on mechanistic synergies and complementary abilities to address different attributes and multiple anatomical layers. Careful consideration should be given to appropriate sequencing. VYC‐12L and non‐ablative EBDs can be used on the same day, but treatment fields must be appropriately managed and aseptic technique rigorously upheld. When administering VYC‐12L, maintaining the correct injection depth is essential to positive outcomes. Practitioners should undertake appropriate training and select the injection tools that optimize control.

Multimodal treatment using VYC‐12L and EBDs together can provide a more comprehensive, tailored approach to skin‐quality improvement, delivering high levels of patient satisfaction.