# Germline Genetic Testing in Patients With Solid Malignant Tumors

**Authors:** Matthew E. Fine, Adina Estrin, Alissa Michel, Vicky Ro, Tarsha Jones, Meghna S. Trivedi, Katherine D. Crew

PMC · DOI: 10.1001/jamanetworkopen.2025.22754 · 2025-07-23

## TL;DR

This study examines who gets genetic testing for inherited cancer risks and their clinical features.

## Contribution

The study provides insights into the patterns and factors associated with germline genetic testing in cancer patients.

## Key findings

- Patients undergoing germline testing often have a family history of cancer.
- Certain tumor types are more frequently associated with genetic testing.
- Demographic factors influence who receives germline genetic testing.

## Abstract

This cohort study analyzes the clinical and demographic characteristics of patients with cancer who undergo germline genetic testing.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** Solid Malignant Tumors (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12287830