# Pulmonary Actinomycosis Causing an Unusual Presentation in a Patient with COPD: A Case Report

**Authors:** Ibrahim Nagmeldin Hassan, Muhsin Nagmeldin Hassan Ibrahim

PMC · DOI: 10.4314/ejhs.v35i3.10 · 2025-05-01

## TL;DR

A 63-year-old COPD patient with poor dental hygiene was diagnosed with pulmonary actinomycosis after presenting with unusual symptoms like pleural effusion.

## Contribution

This case report presents a rare presentation of pulmonary actinomycosis causing pleural effusion in a COPD patient.

## Key findings

- Histopathological analysis confirmed pulmonary actinomycosis with yellow sulfur granules.
- Treatment with amoxicillin/sulbactam followed by oral amoxicillin was effective.
- The case highlights the importance of considering actinomycosis in patients with atypical respiratory symptoms.

## Abstract

We present the case of a 63-year-old male patient with a history of chronic obstructive pulmonary disease (COPD), heavy smoking, and poor dental hygiene, who presented with progressive dyspnea, fever, and a productive cough. The patient was initially evaluated for pneumonia, but a chest radiograph revealed a right-sided pleural effusion. Further analysis of the pleural fluid showed an exudative effusion. Histopathological examination of a pleural biopsy sample identified gram-positive branching filamentous rods with yellow sulfur granules, consistent with a diagnosis of pulmonary actinomycosis. The patient was initially treated with intravenous amoxicillin/sulbactam, later switched to oral amoxicillin. This case highlights a rare clinical presentation of pleural effusion in a patient with pulmonary actinomycosis.

## Linked entities

- **Diseases:** chronic obstructive pulmonary disease (MONDO:0005002)

## Full-text entities

- **Diseases:** effusion (MESH:D000080324), COPD (MESH:D029424), pneumonia (MESH:D011014), dyspnea (MESH:D004417), pleural effusion (MESH:D010996), fever (MESH:D005334), Pulmonary Actinomycosis (MESH:D000196), cough (MESH:D003371)
- **Chemicals:** amoxicillin/sulbactam (-), amoxicillin (MESH:D000658), sulfur (MESH:D013455)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12287713/full.md

---
Source: https://tomesphere.com/paper/PMC12287713