# An Extracranial, Infratemporal Meningioma Following Neoadjuvant Radiotherapy: A Case Report

**Authors:** Luke Borg, David Borg, Bernard Galea, Herman Borg Xuereb

PMC · DOI: 10.7759/cureus.86612 · 2025-06-23

## TL;DR

A rare case of a meningioma tumor developed in a man's face over ten years after he received radiation therapy for a different condition.

## Contribution

This case report presents a rare instance of an extracranial meningioma following neoadjuvant radiotherapy.

## Key findings

- A 66-year-old male developed a meningioma in the infratemporal fossa after cranial radiotherapy for acromegaly.
- Surgical excision using a modified Blair approach preserved the facial nerve.
- Histology confirmed a WHO Grade I meningioma with no intracranial extension.

## Abstract

Extracranial meningiomas are uncommon tumors and represent an unusual manifestation of a typically intracranial disease. While most are intracranial, primary extracranial presentations may arise independently or represent extensions of intracranial disease. Radiation exposure is a recognized but uncommon risk factor. We present a case of a 66-year-old male patient who developed a painless, preauricular mass more than a decade after cranial radiotherapy for acromegaly. Imaging revealed a well-circumscribed, enhancing lesion centered in the infratemporal fossa, with bony remodeling but no intracranial extension. Surgical excision was performed using a modified Blair approach, preserving the facial nerve. Histology confirmed a WHO Grade I meningioma. This case highlights the importance of long-term follow-up in irradiated patients and the value of multidisciplinary planning for complex skull base tumors.

## Linked entities

- **Diseases:** acromegaly (MONDO:0019933), meningioma (MONDO:0003057)

## Full-text entities

- **Diseases:** acromegaly (MESH:D000172), skull base tumors (MESH:D019292), tumors (MESH:D009369), Extracranial meningiomas (MESH:D008579), intracranial disease (MESH:D020765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12286761/full.md

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Source: https://tomesphere.com/paper/PMC12286761