# Adaptation of Risk Score for Hepatocellular Carcinoma Without Alcohol Measures

**Authors:** Janet P. Tate, Tamar H. Taddei, Vincent Lo Re, Amy C. Justice

PMC · DOI: 10.1001/jamanetworkopen.2025.22305 · 2025-07-22

## TL;DR

This study checks if a liver cancer risk score works well without considering alcohol use in veterans.

## Contribution

Validates a hepatocellular carcinoma risk score excluding alcohol measures in veterans.

## Key findings

- Risk scores without alcohol measures were validated in veterans with alcohol use disorder.
- The scores showed acceptable performance for hepatocellular carcinoma detection.
- Results suggest potential for broader clinical applicability in diverse patient groups.

## Abstract

This diagnostic study validates hepatocellular carcinoma risk scores without alcohol measures in veterans with and without alcohol use disorder.

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Diseases:** Hepatocellular Carcinoma (MESH:D006528)
- **Chemicals:** Alcohol (MESH:D000438)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12284736/full.md

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Source: https://tomesphere.com/paper/PMC12284736