# The role of the cingulum in deep brain stimulation of the limbic pain matrix

**Authors:** Thomas Kinfe

PMC · DOI: 10.1093/braincomms/fcaf225 · 2025-06-07

## TL;DR

This commentary discusses the cingulum's role in deep brain stimulation for chronic pain.

## Contribution

It highlights the cingulum as a potential target for treating intractable pain.

## Key findings

- The cingulum is identified as a central area in the limbic pain matrix.
- Its anatomy and connectivity suggest a key role in pain modulation.

## Abstract

This scientific commentary refers to ‘The cingulum: a central hotspot for the battle against chronic intractable pain?’, by Kollenburg et al. (https://doi.org/10.1093/braincomms/fcae368) and ‘The cingulum: anatomy, connectivity and what goes beyond’, by Kollenburg et al. (https://doi.org/10.1093/braincomms/fcaf048).

## Full-text entities

- **Diseases:** pain (MESH:D010146)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12284389/full.md

---
Source: https://tomesphere.com/paper/PMC12284389