Role of Allium cepa and Allium sativum extracts in oxidative stress, sperm parameters and histological abnormalities induced by deep-frying oil in testis
Mohamed Anwer Mohamed, Safa Hamdy Alkalash, Samah Baleegh Meawad, Mohamed Nafea Azab, Marwa A. Ahmed, Ahmad Gadalla, Muhammed Abdelbaeth Hassan Elfiky, Abdel Rahman Z. Abdel Rahman, Hatem Ali Ahmed Abdelmottaleb, Ayman Sabry Yassin Al Sayed, Wafaa Yahia Alghonemy, Amira Osman
TL;DR
This study shows that Allium cepa and Allium sativum extracts can protect rat testes from oxidative stress and damage caused by repeatedly heated deep-frying oil.
Contribution
The novel finding is that combining Allium cepa and Allium sativum extracts provides significant antioxidant protection against testicular damage from deep-frying oil.
Findings
Repeatedly heated oil caused oxidative stress and testicular damage in rats.
Allium cepa and Allium sativum extracts improved oxidative stress markers and sperm parameters.
Combined treatment showed the strongest protective effect on testicular histology.
Abstract
Palm oil is commonly used for deep-frying street food preparation. Extremely vulnerable to oxidative stress and free radicals is testicular tissue. Antioxidant supplements are advised for reducing oxidative stress, boosting spermatogenesis, and neutralizing free radicals. The study evaluated the beneficial role of Allium cepa L(AcL) and Allium sativum L (AsL) extracts in oxidative stress, histopathological, and sperm parameters abnormalities induced by deep-frying palm olein oil in rat testis. Approximately 5 kg of falafel dough tablets were daily deep-fried in oil. For three days, the frying procedure required six hours per day. The animals received daily treatment for four weeks after being split into equal groups (control, AcL, AsL, fresh palm oil (FPO), single heated palm oil (SHPO), repeated heated palm oil (RHPO), AcL + RHPO, AsL + RHPO, and AcL + AsL + RHPO). Serum testosterone…
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Taxonomy
TopicsGarlic and Onion Studies · Sperm and Testicular Function · Sesame and Sesamin Research