# Editorial: Molecular chaperones and polyamines in disease

**Authors:** Stanley Makumire, Graham Chakafana, Xolani H. Makhoba

PMC · DOI: 10.3389/fmolb.2025.1658176 · 2025-07-09

## Full-text entities

- **Genes:** HSP90AB1 (heat shock protein 90 alpha family class B member 1) [NCBI Gene 3326] {aka D6S182, HSP84, HSP90B, HSPC2, HSPCB}, FIRRE (firre intergenic repeating RNA element) [NCBI Gene 286467] {aka LINC01200}, HSP90AA1 (heat shock protein 90 alpha family class A member 1) [NCBI Gene 3320] {aka EL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N}, HSPA4 (heat shock protein family A (Hsp70) member 4) [NCBI Gene 3308] {aka APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70}
- **Diseases:** prion (MESH:D017096), IPS (MESH:C536271), neuroinflammation (MESH:D000090862), neurodegenerative diseases (MESH:D019636), neurological disorders (MESH:D009461), cancer (MESH:D009369), inflammatory (MESH:D007249), pain (MESH:D010146), HCC (MESH:D006528), metastasis (MESH:D009362)
- **Chemicals:** SW02 (-), putrescine (MESH:D011700), spermidine (MESH:D013095), Polyamines (MESH:D011073), spermine (MESH:D013096)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12283322