# Unusual association of primary parotid and conjunctival tuberculosis in a young immunocompetent patient: a case report

**Authors:** Mariam Hachimi Idrissi, Qamar Zaza, Adam Benbachir, Oumaima Skalante, Soufiane Benaazza, Mohamed Allaoui, Yassine Ben Lahlou, Elmostafa Benaissa, Mariama Chadli

PMC · DOI: 10.1099/acmi.0.000982.v3 · Access Microbiology · 2025-07-10

## TL;DR

A young, healthy person had rare tuberculosis in the parotid gland and eye, diagnosed using advanced testing and treated successfully.

## Contribution

Reports a rare case of primary parotid and conjunctival tuberculosis in an immunocompetent patient, emphasizing the role of GeneXpert in diagnosis.

## Key findings

- Primary tuberculosis in the parotid gland and conjunctiva is exceptionally rare and challenging to diagnose.
- GeneXpert proved to be a rapid and effective diagnostic tool for this case of extrapulmonary tuberculosis.
- The patient responded well to anti-bacillary treatment after accurate diagnosis.

## Abstract

Extrapulmonary tuberculosis often presents as lymphadenitis. In the head and neck area, tuberculous involvement of the parotid gland is rare and challenging to diagnose due to non-specific symptoms, which can be confused with a tumour. Tuberculous conjunctivitis, although uncommon, should be considered in cases of chronic, treatment-resistant conjunctivitis. The association of primary parotid and conjunctival tuberculosis is exceptional. They are difficult to diagnose due to the non-specificity of their clinical, biological and radiological signs. We report the case of a 24-year-old immunocompetent patient with no history of tuberculosis, who presented with intermittent swelling of the left parotid gland, accompanied by unilateral redness of the eye, which appeared 2 months later, in a context of fever and night sweats. The patient also reported a foreign body sensation in his eye, mild tearing and photophobia. Clinical examination revealed painful, warm swelling of the left parotid gland, as well as localized granulomatous conjunctivitis. Cervico-parotid CT and MRI revealed two well-limited, oval, left parotid formations with a slightly thickened and enhanced wall after injection of gadolinium, suggestive a priori of abscessed collections. The diagnosis of primary parotid and conjunctival tuberculosis was made on the basis of histological examination of the biopsies, as well as direct examination, culture and GeneXpert. The patient progressed well on anti-bacillary treatment. Our work underlines the great importance of GeneXpert, which is a rapid and highly sensitive technique, effective in the diagnosis of extrapulmonary tuberculosis.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), conjunctivitis (MONDO:0003799)

## Full-text entities

- **Diseases:** granulomatous (MESH:D013968), photophobia (MESH:D020795), swelling (MESH:D004487), tuberculosis (MESH:D014376), fever (MESH:D005334), abscessed collections (MESH:D000038), Tuberculous conjunctivitis (MESH:D003231), tumour (MESH:D009369), parotid and conjunctival tuberculosis (MESH:D010309), lymphadenitis (MESH:D008199), Extrapulmonary tuberculosis (MESH:D000092225)
- **Chemicals:** gadolinium (MESH:D005682)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12282047/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12282047/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12282047/full.md

---
Source: https://tomesphere.com/paper/PMC12282047