# Disseminated tuberculosis with rare coccygeal involvement: a case report

**Authors:** Sarra Baziaa, Adil Zegmout, Mohamed Beaouiss, Soufiane El Fathi, Aniss Rafik, Hicham Souhi, Ismail Rhorfi, Hanane El Ouazzani

PMC · DOI: 10.1099/acmi.0.000924.v3 · Access Microbiology · 2025-06-30

## TL;DR

This case report describes a rare instance of tuberculosis affecting the coccygeal region in a 64-year-old diabetic patient, successfully diagnosed and treated with non-invasive methods.

## Contribution

The novelty lies in the rare coccygeal TB localization in an immunocompetent individual, diagnosed non-invasively.

## Key findings

- TB was diagnosed using Xpert MTB/RIF, confirming Mycobacterium tuberculosis infection.
- The patient showed complete symptom resolution after starting anti-TB therapy.
- The case emphasizes the importance of considering rare TB locations in diagnostic evaluations.

## Abstract

Tuberculosis (TB) is a preventable and usually curable disease but remains a major health problem worldwide, particularly in developing countries. TB of the lumbosacral junction is rare and occurs in only 1–2% of all cases of spinal TB. Moreover, isolated sacrococcygeal TB is extremely rare. We present a case of a 64-year-old patient with a history of diabetes who presented with chronic back pain and cough. Physical examinations revealed a perianal fistula and left elbow joint arthritis. The patient is diagnosed with disseminated TB with coccygeal involvement. Diagnosis was achieved non-invasively using Xpert MTB/RIF, confirming Mycobacterium tuberculosis infection. The patient experienced complete resolution of symptoms following the commencement of anti-TB therapy. We highlight the importance of this case due to the rare coccygeal localization of TB in an immunocompetent patient, diagnosed through non-invasive means.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), elbow joint (MESH:D000092464), arthritis (MESH:D001168), Mycobacterium tuberculosis infection (MESH:D014376), chronic back pain (MESH:D059350), cough (MESH:D003371), perianal fistula (MESH:D000694), spinal TB (MESH:D014399)
- **Chemicals:** Xpert (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12281794/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12281794/full.md

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Source: https://tomesphere.com/paper/PMC12281794