# Primary iliac bone tuberculosis: a case report

**Authors:** Hajar Dahou, Fataou Saley Younoussa, Imane Aragon, Salma El Aouadi, Yahya El Harras, Elmostafa Benaissa, Yassine Ben Lahlou, Abdelaali Bahadi, Jamal El Fenni, Adil Maleb, Mariama Chadli, Mostafa Elouennass

PMC · DOI: 10.1099/acmi.0.000844.v3 · Access Microbiology · 2025-05-07

## TL;DR

This paper presents a rare case of primary iliac bone tuberculosis in a 63-year-old patient, highlighting the challenges in diagnosis and the role of advanced molecular tools like GeneXpert®.

## Contribution

The novelty lies in reporting a rare case of primary iliac bone TB and demonstrating the effectiveness of GeneXpert® in confirming the diagnosis.

## Key findings

- Primary iliac bone TB is rare and can mimic other bone diseases, making diagnosis difficult.
- GeneXpert® on a gluteal collection sample confirmed TB, aiding in rapid and accurate diagnosis.
- The patient had a complex medical history, including diabetes and kidney disease, complicating management.

## Abstract

Tuberculosis (TB) remains one of the world’s leading causes of morbidity and mortality. It occurs in both pulmonary and extra-pulmonary forms. Primary iliac bone TB remains a rare clinical entity, even in endemic areas. The diagnosis of the disease can be challenging due to its similarity to other bone diseases. We report a rare case of primary iliac bone TB in a 63-year-old patient who was on peritoneal dialysis and had a medical history of hypertension and type II diabetes, which was complicated by diabetic retinopathy and diabetic kidney disease. Magnetic resonance imaging revealed osteomyelitis in the iliac bone, while real-time polymerase chain reaction using the GeneXpert® system on a gluteal collection sample confirmed the diagnosis of TB. The integration of advanced molecular tools, such as GeneXpert®, represents significant progress, enabling rapid and accurate diagnosis of TB and facilitating early initiation of treatment.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), type II diabetes (MONDO:0005148), diabetic retinopathy (MONDO:0005266), diabetic kidney disease (MONDO:0005016)

## Full-text entities

- **Diseases:** type II diabetes (MESH:D003924), Primary (MESH:D010538), TB (MESH:D014376), osteomyelitis (MESH:D010019), diabetic retinopathy (MESH:D003930), bone diseases (MESH:D001847), Primary iliac bone tuberculosis (MESH:D014394), hypertension (MESH:D006973), diabetic kidney disease (MESH:D003928)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12281756/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12281756/full.md

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Source: https://tomesphere.com/paper/PMC12281756