# Safety of Vancomycin Use Through Midline Catheters for Outpatient Parenteral Antimicrobial Therapy

**Authors:** David Paje, Emily Walzl, Megan Heath, Elizabeth McLaughlin, Jennifer K. Horowitz, Caitlin Tatarcuk, Lakshmi Swaminathan, Scott Kaatz, Anurag N. Malani, Ashwin Gupta, Valerie M. Vaughn, Steven J. Bernstein, Scott A. Flanders, Vineet Chopra

PMC · DOI: 10.1001/jamainternmed.2025.3110 · JAMA Internal Medicine · 2025-07-21

## TL;DR

This study investigates whether using vancomycin through midline catheters in outpatient settings causes device-related complications.

## Contribution

The study provides new evidence on the safety of administering vancomycin via midline catheters in outpatient care.

## Key findings

- Vancomycin use through midline catheters was not significantly associated with increased device-related complications.
- Patients receiving vancomycin via midline catheters had similar complication rates to those on other antimicrobials.

## Abstract

This cohort study examines the association between vancomycin use through midline catheters and device-related complications among patients receiving outpatient parenteral antimicrobial therapy.

## Linked entities

- **Chemicals:** vancomycin (PubChem CID 14969)

## Full-text entities

- **Chemicals:** Vancomycin (MESH:D014640)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12281390/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12281390/full.md

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Source: https://tomesphere.com/paper/PMC12281390