# A Diagnostic and Management Challenge in Severe Fatal Mercury Poisoning Secondary to Homeopathic Medications

**Authors:** Harry Edgar-Whelan, Eleanor Fish, Phyoe Kyaw Pyae, Hakim Ghani, Rama Vancheeswaran

PMC · DOI: 10.7759/cureus.86514 · Cureus · 2025-06-22

## TL;DR

A patient with rheumatoid arthritis died from severe mercury poisoning likely caused by unregulated Ayurvedic homeopathic medications.

## Contribution

Highlights the risks of unregulated Ayurvedic medications and the need for detailed drug history in clinical practice.

## Key findings

- Chronic mercury poisoning from Ayurvedic medicine led to severe nephrotic syndrome and end-stage renal failure.
- The patient's condition deteriorated despite treatment, resulting in death from respiratory failure.
- The case underscores the importance of inquiring about alternative medication use in patient history.

## Abstract

We present a case of a patient known to have rheumatoid arthritis with severe nephrotic syndrome very likely due to chronic mercury poisoning. She was known to have rheumatoid arthritis for 10 years. Mercury poisoning was attributed to homeopathic Ayurvedic medicine which she took for arthritic pain. It is highly likely that the Ayurvedic medications contained high concentrations of mercury. The patient presented with worsening breathlessness on exertion and global pitting oedema. Initial investigations suggested a nephrotic syndrome of unknown aetiology. The patient’s kidney function worsened, and she developed a hospital-acquired infection and deteriorated further with type 1 respiratory failure. Despite attempted continuous veno-venous hemodiafiltration, the patient unfortunately passed away secondary to end-stage renal failure caused by chronic severe mercury poisoning. This case report adds to the concerns regarding the potential risks of unregulated Ayurvedic medications without clear instructions from a trained medical professional. It highlights the importance of taking a detailed drug history on the first encounter with the patient.

## Linked entities

- **Chemicals:** mercury (PubChem CID 23931)
- **Diseases:** rheumatoid arthritis (MONDO:0008383), nephrotic syndrome (MONDO:0005377), end-stage renal failure (MONDO:0004375)

## Full-text entities

- **Diseases:** oedema (MESH:C536897), Mercury Poisoning (MESH:D008630), end-stage renal failure (MESH:D007676), type 1 respiratory failure (MESH:D012131), arthritic pain (MESH:D010146), nephrotic syndrome (MESH:D009404), breathlessness (MESH:D004417), infection (MESH:D007239), rheumatoid arthritis (MESH:D001172)
- **Chemicals:** mercury (MESH:D008628)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12281050/full.md

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Source: https://tomesphere.com/paper/PMC12281050