# Extraarticular distal humeral nonunion: systematic review of literature

**Authors:** Giovanni Vicenti, Enrico Guerra, Elisa Pesare, Giulia Colasuonno, Marco Minerba, Michele Loiodice, Francesco Conte, Paolo Sergi, Giuseppe Solarino

PMC · DOI: 10.1186/s10195-025-00861-y · Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology · 2025-07-21

## TL;DR

This paper reviews surgical treatments for nonunion fractures in the lower arm, comparing success rates and outcomes of different procedures.

## Contribution

The study systematically reviews and compares surgical techniques for treating extraarticular distal humeral nonunions, emphasizing patient-specific approaches.

## Key findings

- ORIF showed a 90% success rate in treating nonunions compared to 74% for TEA.
- Functional outcomes were similar between ORIF and TEA despite higher healing rates with ORIF.
- TEA is recommended for patients with poor bone quality or complex fractures.

## Abstract

Distal humeral fractures accounted for ~1% of all fractures; however, they were prone to complications, including nonunion if left untreated or inadequately managed. Nonunion, which predominantly occurred at the supracondylar level, resulted in mechanical instability, functional impairment, and persistent discomfort. The most commonly employed surgical options included open reduction and internal fixation (ORIF), total elbow arthroplasty (TEA), and external fixation. This article provides a comprehensive assessment of these surgical procedures and shared clinical experiences related to these challenging cases.

A systematic review of literature was conducted using the PubMed database up to October 2024, with a focus on cases involving extraarticular distal humeral nonunions that were treated with ORIF, TEA, or Ilizarov techniques.

A total of 25 studies involving 448 patients were encompassed in the review, with a mean patient age of 50 years and an average follow-up period of 48 months. Reported success rates for ORIF and TEA were 90% and 74%, respectively. A higher rate of fracture healing was demonstrated by ORIF, although functional outcomes were found to be comparable between the techniques. Complications such as infections and reduced range of motion (ROM) were documented.

The highest success rate in treating aseptic nonunions was associated with ORIF, highlighting the importance of stable fixation, bone grafting, and meticulous preoperative planning. TEA was regarded as a viable option, particularly for patients with poor bone quality or complex, unreconstructible fractures. To optimize outcomes, surgical techniques were required to be customized on the basis of patient-specific factors and surgeon expertise. Further research is recommended to facilitate the comparison of long-term functional outcomes across different surgical approaches.

Level of evidence: IV.

The online version contains supplementary material available at 10.1186/s10195-025-00861-y.

## Full-text entities

- **Diseases:** humeral (MESH:D006810), Nonunion (MESH:C538144), Distal humeral fractures (MESH:D000092483), fracture (MESH:D050723), infections (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12279640/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12279640/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12279640/full.md

---
Source: https://tomesphere.com/paper/PMC12279640