# Pet cancer cases and patterns of treatment at a Spanish veterinary teaching hospital: a retrospective study from 2015 to 2024

**Authors:** Beatriz Romero, Julen Susperregui, Raquel Díez, E. Milena Vazquez, Cristina Lopez, Raúl de la Puente, M. Jose Diez, Nelida Fernandez, Jose M. Rodriguez-Altonaga, Ana M. Sahagun

PMC · DOI: 10.3389/fvets.2025.1588840 · Frontiers in Veterinary Science · 2025-07-08

## TL;DR

This study analyzed cancer cases in pets at a Spanish veterinary hospital from 2015 to 2024, focusing on tumor types, treatment methods, and outcomes.

## Contribution

The study provides a detailed retrospective analysis of pet cancer cases in Spain, including treatment patterns and tumor characteristics.

## Key findings

- Most cancer cases were in dogs, females, and purebred animals, with epithelial tumors being the most common.
- Surgery and chemotherapy were the primary treatments, with protein kinase inhibitors being the main drug class used.
- Euthanasia was performed in nearly 27% of the cases, highlighting the severity of the disease in pets.

## Abstract

Cancer is one of the most common causes of death for companion animals. The study aimed to describe the characteristics of the clinical cases of pets attending at the Veterinary Teaching Hospital (University of Leon, Spain) and diagnosed with tumors. A retrospective study was carried out between 2015 and 2024. A total of 123 animals comprising 107 dogs and 16 cats were obtained from the clinical records. A mean annual incidence risk of 530 of 100,000 animals was calculated. Most animals were dogs (87.0%), females (62.6%), purebred (77.2%) and aged (78.9%). Tumors were mainly malignant (87.8%), they were of epithelial origin (40.7%), and mostly located in mammary glands (27.6%) or skin/mucosa (26.8%). Carcinoma (35.8%) and lymphoma (19.5%) were the major histological types. Almost half of the animals underwent surgical treatment (42.3%). Chemotherapy was administered to 37.4% of the animals, mostly by the oral route. QL01E (protein kinase inhibitors) was the main pharmacological group employed. Concomitant treatments and dietary supplements were also used. Euthanasia was applied to 26.8% of the animals.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)
- **Species:** Canis lupus familiaris (taxon 9615), Felis catus (taxon 9685)

## Full-text entities

- **Diseases:** death (MESH:D003643), Cancer (MESH:D009369), lymphoma (MESH:D008223)
- **Chemicals:** QL01E (-)
- **Species:** Felis catus (cat, species) [taxon 9685], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12279513/full.md

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Source: https://tomesphere.com/paper/PMC12279513