# Orbital Metastasis from Hidradenocarcinoma

**Authors:** Mary Stephen, Kumaradarshini Maruthachalam, Nirupama Kasturi, Jayasri Periyandavan

PMC · DOI: 10.22336/rjo.2025.46 · 2025-04-01

## TL;DR

This paper reports a rare case of a skin tumor spreading to the eye area, highlighting its unusual presentation and impact on vision.

## Contribution

The novelty lies in documenting a rare orbital metastasis from hidradenocarcinoma with optic nerve involvement.

## Key findings

- Hidradenocarcinoma can metastasize to the orbit and extraocular muscles.
- The tumor infiltrated the inferior rectus muscle and involved the optic nerve in this case.
- Orbital metastasis from hidradenocarcinoma is uncommon and presents diagnostic challenges.

## Abstract

Hidradenocarcinoma is a rare form of malignant adnexal tumor. This malignant tumor has been reported to metastasize to regional lymph nodes, and distant metastasis into structures like the orbit and extraocular muscle is uncommon. Orbital metastasis comprises about 10% of all orbital neoplasms. Common systemic malignancies contributing to orbital metastasis are breast cancer, prostate cancer, and skin malignancy, melanoma. We report the case of a middle-aged man with left axillary hidradenocarcinoma with an orbital metastatic lesion infiltrating the inferior rectus muscle with optic nerve involvement. This case report describes a rare presentation of orbital metastasis from an adnexal tumour.

## Linked entities

- **Diseases:** hidradenocarcinoma (MONDO:0006245), breast cancer (MONDO:0004989), prostate cancer (MONDO:0005159), melanoma (MONDO:0005105)

## Full-text entities

- **Diseases:** melanoma (MESH:D008545), orbital neoplasms (MESH:D009918), adnexal tumour (MESH:D009369), breast cancer (MESH:D001943), prostate cancer (MESH:D011471), malignant adnexal tumor (MESH:D000292), Orbital Metastasis (MESH:D009362)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12277994/full.md

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Source: https://tomesphere.com/paper/PMC12277994