# Hemosuccus Pancreaticus: A Challenging Diagnosis and Complex Management

**Authors:** Ahmed Hassanien, Abdullah Motam

PMC · DOI: 10.7759/cureus.86403 · 2025-06-19

## TL;DR

Hemosuccus pancreaticus is a rare and difficult-to-diagnose condition causing upper gastrointestinal bleeding linked to pancreatic issues.

## Contribution

The paper highlights a complex case emphasizing the need for clinical vigilance and multidisciplinary care in managing this rare condition.

## Key findings

- HP is often misdiagnosed due to non-specific symptoms like intermittent bleeding and epigastric pain.
- Prompt diagnosis and management are crucial to reduce high morbidity and mortality risks.
- Multidisciplinary coordination is essential for effective treatment in patients with multiple comorbidities.

## Abstract

Hemosuccus pancreaticus (HP) is an uncommon and infrequently reported cause of upper gastrointestinal bleeding. It is defined as a hemorrhage into the pancreatic duct, which subsequently drains into the duodenum via the ampulla of Vater. The condition is typically associated with underlying pancreatic pathology, such as pancreatitis, pseudocysts, or vascular abnormalities, including splenic artery aneurysms. Clinically, HP presents with intermittent gastrointestinal bleeding, epigastric pain, and a drop in hemoglobin levels; features that often delay diagnosis due to their non-specific and episodic nature. Early recognition is essential, as the condition carries a high risk of morbidity and mortality if not promptly managed. We present a diagnostically challenging case of HP in a frail patient with multiple comorbidities, highlighting the importance of clinical vigilance and multidisciplinary coordination.

## Linked entities

- **Diseases:** pancreatitis (MONDO:0004982)

## Full-text entities

- **Diseases:** vascular abnormalities (MESH:D014652), splenic artery aneurysms (MESH:D013158), pseudocysts (MESH:D010192), pancreatic (MESH:D010195), hemorrhage (MESH:D006470), gastrointestinal bleeding (MESH:D006471), epigastric pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12277924/full.md

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Source: https://tomesphere.com/paper/PMC12277924