# Reprogramming aging: genetically enhanced mesenchymal progenitor cells show systemic rejuvenation in primates

**Authors:** Hongkun Wang, Yuanyuan Du

PMC · DOI: 10.1093/lifemedi/lnaf022 · 2025-06-19

## Full-text entities

- **Genes:** SRC (SRC proto-oncogene, non-receptor tyrosine kinase) [NCBI Gene 6714] {aka ASV, SRC1, THC6, c-SRC, p60-Src}, FOXO3 (forkhead box O3) [NCBI Gene 2309] {aka AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A}
- **Diseases:** periodontal degeneration (MESH:D010518), SRCs (MESH:D002292), tumorigenicity (MESH:D002471), inflammation (MESH:D007249)
- **Chemicals:** SRCs (-), spermine (MESH:D013096)
- **Species:** Homo sapiens (human, species) [taxon 9606], Cercopithecidae (monkey, family) [taxon 9527], Mus musculus (house mouse, species) [taxon 10090]
- **Mutations:** S253A, S315A

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12277565/full.md

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Source: https://tomesphere.com/paper/PMC12277565