# Risk factors for catheter-related bloodstream infections in a high-risk cancer patient population

**Authors:** Andrea Haddad, Rita Wilson Dib, Anne-Marie Chaftari, Ying Jiang, Mohamed Moussa, Hiba Dagher, Ann Philip, Ray Hachem, Issam Raad

PMC · DOI: 10.1017/ice.2025.45 · 2025-05-26

## TL;DR

This study identifies risk factors for catheter-related bloodstream infections in cancer patients and suggests that catheter site selection can help reduce infection risk.

## Contribution

The study identifies specific risk factors for CRBSI in high-risk cancer patients and highlights the protective effect of jugular catheter insertion.

## Key findings

- Neutropenia, transplants, and multiple catheters increase CRBSI risk.
- Jugular insertion is associated with a lower risk of CRBSI.
- Catheter site selection can be a strategy to reduce infection risk.

## Abstract

To identify risk factors for catheter-related bloodstream infections (CRBSI) in cancer patients, we compared 200 CRBSI cases to 400 controls. Neutropenia, transplants, multiple catheters, blood products, and basilic/cephalic PICCs increased CRBSI risk, while jugular insertion was protective. Catheter site selection can reduce risk. Other targeted strategies are warranted.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** bloodstream infections (MESH:D018805), cancer (MESH:D009369), Neutropenia (MESH:D009503)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12277075/full.md

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Source: https://tomesphere.com/paper/PMC12277075