# Seizure Occurrence During Hyperbaric Oxygen Therapy: A Case Report and Literature Review

## TL;DR

An 88-year-old patient had a seizure during hyperbaric oxygen therapy for bladder complications, showing the potential neurological risks of the treatment.

## Contribution

Reports a new-onset seizure during first hyperbaric oxygen therapy session in an elderly patient.

## Key findings

- Seizure occurred during initial hyperbaric oxygen therapy session in an 88-year-old patient.
- Hyperbaric oxygen therapy may carry neurological risks despite its therapeutic benefits.
- Case highlights the need to balance treatment benefits with potential adverse effects.

## Abstract

Pelvic radiotherapy can lead to lasting bladder complications such as radiation-induced hemorrhagic cystitis. Hyperbaric oxygen therapy has emerged as a worthwhile intervention, enhancing tissue oxygenation and promoting neovascularization. However, hyperbaric oxygen therapy carries the risk of seizures, particularly with prolonged exposure to elevated pressures. In this case report, we describe a case of new-onset seizure occurrence in an 88-year-old patient during their first session of hyperbaric oxygen therapy for treatment of radiation-induced hemorrhagic cystitis, highlighting the complexities of balancing therapeutic benefits with potential neurological risks.