# Spontaneous Rupture of Hepatocellular Adenoma During Pregnancy Complicated by Intrauterine Fetal Death

**Authors:** Ariana Bárbara, Cassandra Lemper, Marcos D'Ippolito, Lutero Jung

PMC · DOI: 10.7759/cureus.86369 · 2025-06-19

## TL;DR

A rare case of a liver tumor rupturing during pregnancy caused severe bleeding and fetal death, highlighting the risks of hepatocellular adenomas in pregnant women.

## Contribution

This case report highlights the rare but life-threatening complication of hepatocellular adenoma rupture during pregnancy.

## Key findings

- Hepatocellular adenoma rupture during pregnancy can lead to maternal hemorrhagic shock and intrauterine fetal death.
- Estrogen may contribute to tumor growth, making pregnancy a high-risk period for rupture.
- Prompt investigation and treatment are essential in such cases.

## Abstract

A very rare cause of intrauterine fetal death through maternal hemorrhagic shock is the rupture of a hepatocellular adenoma (HCA) during pregnancy. Estrogens appear to contribute to the growth of the mass, which makes pregnancy a vulnerable period for an emergency associated with such masses. Rupture of HCA is potentially life-threatening and should lead to prompt investigation and treatment. We present a case of a primigravida, at term, admitted hemodynamically unstable from hemorrhagic shock due to a rupture of a hepatocellular adenoma.

## Linked entities

- **Diseases:** hepatocellular adenoma (MONDO:0018902), intrauterine fetal death (MONDO:0041526)

## Full-text entities

- **Diseases:** Intrauterine Fetal Death (MESH:D005313), HCA (MESH:D018248), hemorrhagic shock (MESH:D012771)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12276025/full.md

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Source: https://tomesphere.com/paper/PMC12276025