# Progressive Cranial Nerve Deficits in Granulomatosis With Polyangiitis: A Case Report

## TL;DR

A 60-year-old woman's progressive cranial nerve issues were linked to GPA, a rare vasculitis, stressing the need for early diagnosis and treatment.

## Contribution

Highlights GPA as a rare cause of progressive cranial neuropathy and emphasizes multidisciplinary diagnosis and treatment.

## Key findings

- GPA can present with progressive cranial nerve deficits, leading to diagnostic challenges.
- Timely immunosuppressive treatment is crucial to prevent chronic effects of GPA.
- Multidisciplinary approaches improve diagnosis and management of GPA-related neuropathy.

## Abstract

Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis that can involve multiple organ systems, including the nervous system. Central nervous system (CNS) involvement, especially in the form of cranial nerve neuropathy, is uncommon and may present with significant diagnostic challenges. This case report details the presentation, diagnostic workup, and management of a 60-year-old female who initially developed unilateral cranial nerve deficits, which progressed to bilateral involvement over an 11-day hospital course. The purpose of this case report is to highlight the importance of including GPA in the differential diagnosis in the setting of progressive cranial neuropathy, and to emphasize the need for a multidisciplinary approach for timely diagnosis and utilization of immunosuppressive treatment to minimize the chronic effects of the disease.