# Ileosigmoid knotting: A rare cause of acute abdomen with fatal outcome in a 60-year-old man: Case report from a resource-limited setting

**Authors:** Dagne Aschenaki Argaw, Wali Ahmed Nur, Musse Ahmed Ibrahim, Mohamed Ayanle Hassan, Aidrose Ahmed Mohamud, Addisu Assfaw Ayen

PMC · DOI: 10.1016/j.ijscr.2025.111641 · 2025-07-09

## TL;DR

A 60-year-old man in Ethiopia died from ileosigmoid knotting, a rare and deadly intestinal obstruction that is hard to diagnose and treat in resource-limited areas.

## Contribution

Highlights the challenges of diagnosing and managing ileosigmoid knotting in low-resource settings with a fatal case report.

## Key findings

- ISK is rare but life-threatening, often leading to high mortality in resource-limited regions.
- Diagnosis is difficult with standard tests, requiring surgical exploration.
- Late presentation and limited healthcare resources worsen outcomes in such cases.

## Abstract

Ileosigmoid knotting(ISK), a rare but life-threatening condition which first described in 1845. It occurred when the ileum twisting around the sigmoid colon and causing intestinal obstruction and potential perforation.

A 60-year-old male from the Garbo region of Somali, Ethiopia, presented to the hospital after a a four-day history of intestinal obstruction symptoms. On examination, he was tachycardic and febrile, and exhibited diffuse abdominal tenderness. A diagnosis of intestinal obstruction with generalized peritonitis was made after abdominal x ray. The patient was resuscitated with fluids, started on antibiotics, and a nasogastric tube was placed. Emergency laparotomy revealed ileosigmoid knotting with gangrenous bowel. En bloc resection of the affected ileum and sigmoid colon was performed. An ileo-jejunal anastomosis and an end colostomy were constructed. Despite these interventions, the patient succumbed to uncontrolled sepsis on the fourth postoperative day.

Ileosigmoid knotting (ISK), a rare and deadly form of intestinal obstruction, is more common in the “volvulus belt” regions like Africa and parts of Asia. It involves a twisted knot of the ileum and sigmoid colon and can be caused by factors like a narrow mesentery or hypermobile ileum. ISK is difficult to diagnose with standard tests and often requires surgical exploration. The mortality is high (up to 48 %), especially in resource-limited settings due to various challenges.

Ileosigmoid knotting is a rare and dangerous cause of intestinal obstruction requiring quick action. Poor outcomes are common, especially in resource-limited areas like Ethiopia due to late presentation and limited healthcare resources.

## Linked entities

- **Diseases:** intestinal obstruction (MONDO:0004565), peritonitis (MONDO:1010128)

## Full-text entities

- **Diseases:** abdominal tenderness (MESH:D000007), febrile (MESH:D000071072), sepsis (MESH:D018805), intestinal obstruction (MESH:D007415), acute abdomen (MESH:D000006), peritonitis (MESH:D010538), volvulus (MESH:D045822)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12275487/full.md

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Source: https://tomesphere.com/paper/PMC12275487