# Efficacy and Value of Antibiotic Allergy Evaluations in a Pediatric Solid Organ Transplant Population

**Authors:** Jim Liu, Timothy G Chow, Rory E Nicolaides

PMC · DOI: 10.1093/ofid/ofaf397 · 2025-07-01

## TL;DR

The study shows that evaluating antibiotic allergies in pediatric organ transplant patients is safe, effective, and economically beneficial.

## Contribution

The novel contribution is demonstrating the safety and economic value of antibiotic allergy evaluations in pediatric solid organ transplant recipients.

## Key findings

- Antibiotic allergy evaluations can be safely performed in pediatric solid organ transplant patients.
- Sulfonamide allergy delabeling was found to have positive economic value.

## Abstract

Antibiotic allergies can complicate the treatment and prophylaxis of bacterial infections in the pediatric solid organ transplant population. This single-center retrospective study revealed that antibiotic allergy evaluations and testing could safely and effectively be performed in this population group, with a positive economic value associated with sulfonamide allergy delabeling.

Graphical Abstract

## Linked entities

- **Chemicals:** sulfonamide (PubChem CID 5333)

## Full-text entities

- **Diseases:** bacterial infections (MESH:D001424), Antibiotic Allergy (MESH:D004761), allergy (MESH:D004342)
- **Chemicals:** sulfonamide (MESH:D013449)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12275090/full.md

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Source: https://tomesphere.com/paper/PMC12275090