# Cancer Risk Concerns and Communication Gaps Regarding GLP-1 Medications

**Authors:** Roxanna Attar-Olyaee, Ramez Kouzy, Michael K. Rooney, Zakaria El-Kouzi, Karen E. Hoffman, Sherif M. Gadoue, Comron J. Hassanzadeh, Junyi Jessy Li, Osama Mohamad

PMC · DOI: 10.1001/jamanetworkopen.2025.21878 · 2025-07-18

## TL;DR

This study examines what patients are saying online about cancer risks from GLP-1 medications and how much they're discussing these concerns with their doctors.

## Contribution

The study provides new insights into patient concerns and communication gaps about cancer risks related to GLP-1 medications.

## Key findings

- Patients frequently express cancer risk concerns about GLP-1 medications on social media.
- There is a notable gap in communication between patients and clinicians regarding these concerns.

## Abstract

This cross-sectional study analyzes social media posts to explore patient concerns and the extent of patient–clinician communication regarding cancer risks associated with glucagon-like peptide-1 (GLP-1) medications.

## Linked entities

- **Proteins:** GCG (glucagon)
- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Genes:** GLP1R (glucagon like peptide 1 receptor) [NCBI Gene 2740] {aka GLP-1, GLP-1-R, GLP-1R}
- **Diseases:** Cancer (MESH:D009369)

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Source: https://tomesphere.com/paper/PMC12274973