# Successful Vaginal Delivery Enabled by Continuous Epidural Analgesia for Cancer-Related Pain in Pregnancy: A Case Report

**Authors:** Risa Miyazaki, Megumi Kanao-Kanda, Toshiyuki Kuriyama, Sarah K Luthe, Tomoyuki Kawamata

PMC · DOI: 10.7759/cureus.86283 · Cureus · 2025-06-18

## TL;DR

A pregnant woman with cancer-related pain successfully delivered vaginally using continuous epidural analgesia, avoiding risky systemic pain medications.

## Contribution

This case report demonstrates the safe use of continuous epidural analgesia for managing cancer-related pain during pregnancy.

## Key findings

- Continuous epidural analgesia allowed the patient to maintain optimal labor positioning and achieve vaginal delivery.
- Postpartum pain was effectively managed with oral opioids without fetal risks.
- The approach enabled timely initiation of oncologic treatment after delivery.

## Abstract

Managing cancer-related pain during pregnancy presents a significant clinical challenge due to the limited use of systemic analgesics, such as opioids and nonsteroidal anti-inflammatory drugs (NSAIDs), owing to the potential risks to the fetus. Severe cancer-related pain may impair a parturient’s ability to assume or maintain an optimal labor positioning during labor and delivery, potentially precluding vaginal delivery. In June 2019, a 32-year-old pregnant woman with synovial sarcoma developed intractable gluteal pain that impaired her ability to assume an appropriate delivery position. Given the concerns regarding the use of systemic opioids and NSAIDs, continuous lumbar epidural analgesia was initiated at 34 weeks' gestation to manage cancer-related pain. This approach enabled the patient to tolerate labor positioning, leading to successful vaginal delivery with minimal discomfort. Postpartum pain was managed with oral opioids, and definitive oncologic treatment was initiated one month after delivery. This case demonstrates that continuous epidural analgesia can serve as an effective and safe strategy to manage cancer-related pain during pregnancy, facilitating vaginal delivery when systemic analgesic use is limited.

## Linked entities

- **Chemicals:** opioids (PubChem CID 126961754)
- **Diseases:** synovial sarcoma (MONDO:0010434)

## Full-text entities

- **Diseases:** Cancer-Related Pain (MESH:D000072716), synovial sarcoma (MESH:D013584), gluteal pain (MESH:C531783), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12273603/full.md

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Source: https://tomesphere.com/paper/PMC12273603