# Acute compartment syndrome following cardiovascular surgery: a rare and catastrophic complication highlighting the importance of early detection and intervention

**Authors:** Xianwen Hu, Youjun Pan, Zhiru Che, Yingya Cao, Xiaogan Jiang, Qiancheng Xu, Weihua Lu

PMC · DOI: 10.1186/s12872-025-04970-8 · BMC Cardiovascular Disorders · 2025-07-18

## TL;DR

Acute compartment syndrome is a rare but severe complication after heart surgery, requiring early detection and quick action to prevent long-term damage.

## Contribution

This case emphasizes the importance of early recognition and intervention in managing acute compartment syndrome after cardiovascular surgery.

## Key findings

- ACS after cardiovascular surgery is rare but can lead to severe complications if not detected early.
- Enhanced monitoring techniques may help in timely diagnosis of ACS in high-risk patients.
- A case of successful recovery after ACS highlights the importance of prompt surgical intervention.

## Abstract

Acute compartment syndrome (ACS) is a critical condition resulting from increased intra-compartmental pressure, causing tissue ischemia and necrosis. ACS following cardiovascular surgery is rare but catastrophic. Postoperative sedation and analgesia often obscure classic symptoms, delaying diagnosis. This underscores the importance of vigilance and early detection, particularly in high-risk scenarios such as prolonged extracorporeal circulation and femoral artery cannulation. Enhanced monitoring, including tissue oxygen saturation and transcutaneous oxygen pressure, may facilitate timely diagnosis.

We report a 56-year-old male who developed ACS after valve replacement surgery involving femoral artery cannulation for cardiopulmonary bypass. Approximately 12 h postoperatively, the patient exhibited severe lower limb swelling, mottling, and diminished dorsalis pedis pulse. Laboratory findings revealed elevated myoglobin and creatine kinase levels. Diagnosis was confirmed via clinical and ultrasound evaluation, prompting emergent fasciotomy. Postoperative management included wound care, renal replacement therapy, and skin flap reconstruction. At 6 months follow-up, the patient achieved complete functional recovery of the affected limb.

ACS is a rare but severe complication of cardiovascular surgery. This case highlights the necessity for heightened vigilance, early recognition, and timely intervention to mitigate adverse outcomes. Further studies are needed to validate and establish standardized monitoring protocols and management strategies, including early use of distal perfusion techniques, to improve surgical safety and patient outcomes.

## Full-text entities

- **Genes:** MB (myoglobin) [NCBI Gene 4151] {aka MYOSB, PVALB}
- **Diseases:** necrosis (MESH:D009336), swelling (MESH:D004487), ACS (MESH:D000208), ischemia (MESH:D007511)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12273471/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12273471/full.md

---
Source: https://tomesphere.com/paper/PMC12273471