# Magnetic Resonance Imaging of Paediatric Orbital Tumors With Pathological Correlation

**Authors:** Deepak Kumar, Umakant Prasad, Rashmi R Bharti, Sulekha Kumari, Amit Kumar, Gyan Bhaskar, Rizwan Ahmar

PMC · DOI: 10.7759/cureus.86255 · Cureus · 2025-06-17

## TL;DR

This study uses MRI to diagnose and classify pediatric orbital tumors, showing that retinoblastoma is the most common and emphasizing the importance of imaging and pathology for early detection.

## Contribution

The study provides a detailed MRI-pathological correlation for pediatric orbital tumors in a clinical setting.

## Key findings

- Retinoblastoma was the most common diagnosis, accounting for 50% of cases.
- MRI helped distinguish between benign and malignant tumors, with 57.8% of cases being malignant.
- Leukocoria was the most common presenting symptom among pediatric patients.

## Abstract

Introduction: Paediatric orbital tumours include a broad spectrum of benign and malignant lesions that range from developmental anomalies to primary and metastatic orbital malignancies. Sometimes, clinical signs and symptoms are not enough to differentiate between orbital lesions; hence, MRI plays a crucial role in cases where clinical and historical findings are inconclusive.

Aims and objectives: The aim of the study is to evaluate the different orbital tumours in paediatric patients by magnetic resonance imaging and their pathological correlation.

Materials and methods: We conducted a prospective observation study of 64 paediatric patients (38 males and 26 females), with an age range of one month to 15 years and a mean of 4.6 years, who underwent orbital MRI for suspected tumors at Indira Gandhi Institute of Medical Science, Patna, a tertiary care center, over a period of one year.

Results: Of 64 patients (mean age 4.6 years), 38 (59.3%) were boys and 26 (40.7%) were girls. The most common presentation in our study is leukocoria (white pupillary reflex), and out of 64 cases, 37 (57.8%) were found malignant and 27 (42.2%) were benign lesions. The most common diagnosis was retinoblastoma (32 cases, 50%). Common benign tumours include dermoid cyst, capillary hemangioma, epidermal inclusion cyst and lipodermoid cyst.

Conclusion: As symptoms are not well appreciated in paediatric orbital tumours, for early diagnosis and staging, excellent imaging (MRI ) and histopathological examination are necessary in order for timely detection and to prevent advanced stage at presentation.

## Linked entities

- **Diseases:** retinoblastoma (MONDO:0008380)

## Full-text entities

- **Diseases:** retinoblastoma (MESH:D012175), epidermal inclusion cyst (MESH:D004814), Orbital Tumors (MESH:D009918), orbital lesions (MESH:D009916), white pupillary reflex (MESH:D011681), developmental anomalies (MESH:C566440), lipodermoid cyst (MESH:D003560), capillary hemangioma (MESH:D018324), benign tumours (MESH:D009369), dermoid cyst (MESH:D003884)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12271958/full.md

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Source: https://tomesphere.com/paper/PMC12271958