# Presumed insect sting–induced Takotsubo cardiomyopathy

**Authors:** Karl Maxemous, Noah D.H. Lewis, Jason Chung, Jumana Sarraj, Samira Jeimy

PMC · DOI: 10.1016/j.jacig.2025.100516 · The Journal of Allergy and Clinical Immunology: Global · 2025-06-11

## TL;DR

The paper describes a rare case of heart issues caused by an insect sting and explores treatment options for a patient with heart conditions.

## Contribution

It presents a novel approach to desensitizing a high-risk patient using modified venom immunotherapy.

## Key findings

- Insect stings can trigger Takotsubo cardiomyopathy, a rare heart condition.
- Modified venom immunotherapy was considered safe and effective for a patient with cardiovascular comorbidities.

## Abstract

This report highlights a rare association between an insect sting and Takotsubo cardiomyopathy. It discusses the decisions surrounding the use and safety of epinephrine and a modified venom immunotherapy approach for desensitizing a high-risk patient with cardiovascular comorbidities.

## Linked entities

- **Diseases:** Takotsubo cardiomyopathy (MONDO:0019018)

## Full-text entities

- **Diseases:** Takotsubo cardiomyopathy (MESH:D054549), cardiovascular (MESH:D002318), insect sting (MESH:D007299)
- **Chemicals:** epinephrine (MESH:D004837)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12271855/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12271855/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12271855/full.md

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Source: https://tomesphere.com/paper/PMC12271855