# Comparison of traumatic brain injury resulting from stair-related falls to falls from standing height—a neurotrauma center cohort

**Authors:** Cathrine Tverdal, Andrew Reiner, Eirik Helseth, Torgeir Hellstrøm, Unn Sollid Manskow, Mads Aarhus, Karoline Skogen, Pål Rønning, Dag Ferner Netteland

PMC · DOI: 10.3389/fneur.2025.1599229 · Frontiers in Neurology · 2025-07-04

## TL;DR

This study compares traumatic brain injuries from stair-related falls and falls from standing height, finding that both lead to poor outcomes, with stair falls more often linked to alcohol and occurring at night.

## Contribution

The study provides a detailed comparison of TBI epidemiology and outcomes between two common fall types using a large registry-based cohort.

## Key findings

- Stair-related falls accounted for 25% of fall-related TBIs and were more common in younger, healthier individuals.
- Stair-related falls occurred more frequently at night, on weekends, and were associated with alcohol use.
- Both fall types resulted in poor functional outcomes for nearly 40% of patients, though the difference was not statistically significant.

## Abstract

Falls are the leading cause of traumatic brain injury (TBI) in high-income countries, and globally, the incidence of fall-related injuries is projected to rise. In this study, we compare TBI resulting from stair-related falls (SRFs) to falls from standing height (FSH), analyzing their epidemiology and outcomes.

In a single-center, registry-based cohort study using the Oslo TBI Registry-Neurosurgery (OTBIR-N), we identified adults (≥18 years) admitted to Oslo University Hospital with TBI from either SRFs or FSH between 2015 and 2022. Epidemiology and outcome measures were compared between the two groups, and a multivariate logistic regression model was used to evaluate the adjusted effect of the fall mechanisms on dichotomized functional outcome (Glasgow outcome score (GOS) 1–3 vs. GOS 4–5).

A total of 1,432 patients with a median age of 71 years were included. SRFs represented 25%, while FSH represented 52% of all fall-related TBIs. SRF patients were generally younger and healthier, with a higher frequency of moderate to severe TBI than FSH patients (53% vs. 31%; p < 0.001). SRFs also occurred more often during evenings and nights, on weekends, and were more often related to alcohol influence (58% vs. 22%; p < 0.001). Both fall types resulted in unfavorable functional outcomes (GOS 1–3) for a substantial proportion of patients (37% in SRFs and 42% in FSH; p = 0.066). When adjusting for covariates in the multivariable logistic regression model, there was a tendency of SRFs being associated with unfavorable outcomes compared to FSH, but the effect was not statistically significant (OR 1.43, 95%CI 0.97–2.12; p = 0.073).

SRFs represented a considerable proportion of fall-related TBIs and were associated with poor outcomes in a substantial proportion of patients. Targeted public awareness campaigns addressing the risks associated with staircases, especially when combined with alcohol influence, seem warranted to prevent such injuries.

## Linked entities

- **Diseases:** traumatic brain injury (MONDO:0858950)

## Full-text entities

- **Diseases:** TBI (MESH:D000070642)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12271176/full.md

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Source: https://tomesphere.com/paper/PMC12271176