# Contact Dermatitis From Exposure to Virginia Creeper (Parthenocissus quinquefolia): A Deviation From the Saying “Leaves of Three, Let It Be”

## TL;DR

A woman developed a rash from touching Virginia creeper, a plant not typically associated with allergic reactions, highlighting the need for broader awareness.

## Contribution

Highlights Virginia creeper as a cause of contact dermatitis, expanding understanding beyond traditional allergenic plants.

## Key findings

- A physician developed a rash from Virginia creeper exposure, similar to poison ivy reactions.
- Symptoms resolved within a month after treatment and plant removal.
- Virginia creeper can cause allergic contact dermatitis despite not fitting common plant allergy patterns.

## Abstract

Phytodermatitis is often caused by contact with certain plants and may be recognized by the common saying, "leaves of three, let it be".  However, lesser-known plants, such as Virginia creeper (Parthenocissus quinquefolia), can also cause significant contact dermatitis (CD).

A 54-year-old female physician with a history of poison ivy allergy presented with a pruritic, erythematous, blistering rash with linear streaks on her face, neck, and arms following exposure to Virginia creeper plants in her backyard. Symptoms began 48 hours post-exposure, exhibiting linear streaks and scattered plaques suggestive of allergic contact dermatitis (ACD). The patient self-treated with topical betamethasone, diphenhydramine, ibuprofen, and petroleum jelly. Symptoms significantly improved within one week, with complete resolution by one month. Removal of Virginia creeper plants from her backyard prevented further recurrence.

Clinicians and the public should be aware that Virginia creeper, despite its five-leaf configuration, can cause phytodermatitis that is very similar to poison ivy. Recognition and identification of plant-induced dermatitis are significant for effective management and prevention.